An Overview of Type 2 Diabetes Mellitus (T2DM): Dental Implant Survival Rates

  • Mefina Kuntjoro Universitas Airlangga
  • Nike Hendrijantini Universitas Airlangga
  • Agus Dahlan Universitas Airlangga
  • Husniya Juwita Farha Universitas Airlangga
  • Mayang Aziza Hanif Ardianto Universitas Airlangga
Keywords: dental implant, uncontrolled T2DM, implant survival, CBCT, ISQ

Abstract

Background: Dental implants are an alternative treatment to replace missing teeth, as it is one of the oral health problems in the elderly. The success of dental implants is affected by a process known as osseointegration. Systemic conditions such as T2DM can interfere with the osseointegration process which can lead to implant failure. As the patient's blood glucose level increases, it will increase the accumulation of AGEs. These AGEs will interfere with the stages of bone-implant contact and also bone growth around the implant Objectives: To review dental implant survival rates in T2DM patients based on HbA1c, ISQ and CBCT examinations. Conclusion: Dental implants in T2DM patients after being evaluated for 2 years showed a good result. This result is obtained with the condition that HbA1c control is below 8%. Another solution to support the success of dental implants placement in T2DM patients is the use of delayed insertion technique and modification of the implant surface with HA or SLA is also recommended. Evaluation of implant success can also be done with pre-operative planning, such as evaluation of the bone condition with ISQ and CBCT examinations.

Author Biographies

Mefina Kuntjoro, Universitas Airlangga
Departement of Prosthodontics, Faculty of Dental Medicine, Universitas Airlangga, Surabaya – Indonesia
Nike Hendrijantini, Universitas Airlangga
Departement of Prosthodontics, Faculty of Dental Medicine, Universitas Airlangga, Surabaya – Indonesia
Agus Dahlan, Universitas Airlangga
Departement of Prosthodontics, Faculty of Dental Medicine, Universitas Airlangga, Surabaya – Indonesia
Husniya Juwita Farha, Universitas Airlangga
Undergraduate Student of the Faculty of Dental Medicine, Universitas Airlangga, Surabaya – Indonesia
Mayang Aziza Hanif Ardianto, Universitas Airlangga
Undergraduate Student of the Faculty of Dental Medicine, Universitas Airlangga, Surabaya – Indonesia

References

CDC. Trends in Dental Caries and Sealants, Tooth Retention, and Edentulism, United States. 2019; Available from: www.cdc.gov/oralhealth

Alghamdi HS, Jansen JA. The development and future of dental implants. Dent Mater J. 2020;39(2):167–72.

American Diabetes Association. Standard medical care in diabetes 2018. J Clin Appl Res Educ. 2018;41(January).

Jelinek HF, Stranieri A, Yatsko A, Venkatraman S. Data analytics identify glycated haemoglobin co-markers for type 2 diabetes mellitus diagnosis. Comput Biol Med [Internet]. 2016;75:90–7. Available from: http://dx.doi.org/10.1016/j.compbiomed.2016.05.005

King S, Klineberg I, Levinger I, Brennan-Speranza TC. The effect of hyperglycaemia on osseointegration: a review of animal models of diabetes mellitus and titanium implant placement. Arch Osteoporos [Internet]. 2016;11(1). Available from: http://dx.doi.org/10.1007/s11657-016-0284-1

Oates TW, Galloway P, Alexander P, Green AV, Huynh-Ba G, Feine J, et al. The effects of elevated hemoglobin A1c in patients with type 2 diabetes mellitus on dental implants: Survival and stability at one year. J Am Dent Assoc. 2014;145(12):1218–26.

H H, G W, E H. The clinical significance of implant stability quotient (ISQ) measurements: A literature review. J Oral Biol Craniofacial Res. 2020;10(4):629–38.

Latimer JM, Roll KL, Daubert DM, Zhang H, Shalev T, Wolff LF, et al. Clinical performance of hydrophilic, titanium-zirconium dental implants in patients with well-controled and poorly controled type 2 diabetes: 1-Year results of a dual-center cohort study. J Periodontol. 2021;(January 2022).

Sargolzaie N, Samizade S, Arab H, Ghanbari H, Khodadadifard L, Khajavi A. The evaluation of implant stability measured by resonance frequency analysis in different bone types. J Korean Assoc Oral Maxillofac Surg. 2019;45(1):29–33.

Ananda N, Dwi Sulistyani L, Winiati Bachtiar E. Pertimbangan Penggunaan Implan Gigi pada Lansia. Insisiva Dent J Maj Kedokt Gigi Insisiva. 2017;6(1):47–55.

Jacobs R, Salmon B, Codari M, Hassan B, Bornstein MM. Cone beam computed tomography in implant dentistry: Recommendations for clinical use. BMC Oral Health. 2018;18(1):1–16.

Vootla DNR, Reddy DKV. Osseointegration- Key Factors Affecting Its Success-An Overview. IOSR J Dent Med Sci. 2017;16(04):62–8.

Galicia-Garcia U, Benito-Vicente A, Jebari S, Larrea-Sebal A, Siddiqi H, Uribe KB, et al. Pathophysiology of type 2 diabetes mellitus. Int J Mol Sci. 2020;21(17):1–34.

Kim B-J, Kim C-H, Kim J-H. Immediate implant placement following tooth extraction with simultaneous lateral sinus augmentation: a retrospective clinical study after at least 1 year of loading. Int J Implant Dent. 2021;7(1).

Clark D, Barbu H, Lorean A, Mijiritsky E, Levin L. Incidental findings of implant complications on postimplantation CBCTs: A cross-sectional study. Clin Implant Dent Relat Res. 2017;19(5):776–82.

Eskow CC, Oates TW. Dental Implant Survival and Complication Rate over 2 Years for Individuals with Poorly Controlled Type 2 Diabetes Mellitus. Clin Implant Dent Relat Res. 2017;19(3):423–31.

Aguilar-Salvatierra A, Calvo-Guirado JL, González-Jaranay M, Moreu G, Delgado-Ruiz RA, Gómez-Moreno G. Peri-implant evaluation of immediately loaded implants placed in esthetic zone in patients with diabetes mellitus type 2: A two-year study. Clin Oral Implants Res. 2016;27(2):156–61.

Juncar RI, Precup AI, Juncar M. Immediate implant-prosthetic dental rehabilitation of patients with diabetes using four immediately loaded dental implants: a pilot study. J Int Med Res. 2020;48(3).

Friedmann A, Winkler M, Diehl D, Yildiz MS, Bilhan H. One-year performance of posterior narrow diameter implants in hyperglycemic and normo-glycemic patients—a pilot study. Clin Oral Investig. 2021;25(12):6707–15.

Sam L, Chattipakorn S, Khongkhunthian P. Osseointegration of maxillary dental implants in diabetes mellitus patients: A randomized clinical trial human histomorphometric study. Appl Sci. 2020;10(19):1–13.

Chambrone L, Palma LF. Current status of dental implants survival and peri-implant bone loss in patients with uncontrolled type-2 diabetes mellitus. Curr Opin Endocrinol Diabetes Obes. 2019;26(4):219–22.

de Souza ACR, Tedesco BAN, Lourenção PLT de A, Terra SA, de Araújo CDRP, Spadella CT, et al. Ultrastructural analysis of bone formation around dental implants in nondiabetic rats, severe diabetics not controlled and controlled with insulin. Acta Cir Bras. 2020;35(11):1–7.

Shin SY, Shin S Il, Kye SB, Hong J, Paeng JY, Chang SW, et al. The effects of defect type and depth, and measurement direction on the implant stability quotient value. J Oral Implantol. 2015;41(6):652–6.

Pramanik F, Firman RN. Interpretasi cone beam computed tomography 3-dimension dalam pemasangan implan dental di Rumah Sakit Gigi Mulut Fakultas Kedokteran Gigi Universitas Padjadjaran. J Dentofasial. 2015;14(1):50–4.

Zhou W, Tangl S, Reich KM, Kirchweger F, Liu Z, Zechner W, et al. The Influence of Type 2 Diabetes Mellitus on the Osseointegration of Titanium Implants with Different Surface Modifications-A Histomorphometric Study in High-Fat Diet/Low-Dose Streptozotocin-Treated Rats. Implant Dent. 2019;28(1):11–9.

Ormianer Z, Block J, Matalon S, Kohen J. The Effect of Moderately Controlled Type 2 Diabetes on Dental Implant Survival and Peri-implant Bone Loss: A Long-Term Retrospective Study. Int J Oral Maxillofac Implants. 2018;33(2):389–94.

Published
2022-12-01